Molecular Typing and Surveillance

We can use the molecular sequences of the viral genomes to categorise them into different types. Viral types are either connected with different viral properties (e.g. virulence) or epidemic history, and molecular typing studies provide important information even for deeper, more basic problems such as the replication mechanism of the virus.

Some publication that we have been engaged with Molecular Typing and Surveillance

- Magiorkinis G. Mouse viruses and human disease. Lancet Infectious Diseases 11:264

- Paraschiv S, Otelea D, Batan I, Baicus C, Magiorkinis G, Paraskevis D. Molecular typing of the recently expanding subtype B HIV-1 epidemic in Romania: evidence for local spread among MSMs in Bucharest area. Infection, Genetics & Evolution 12:1052-7

- Katsoulidou A, Sypsa V, Tassopoulos NC, Boletis J, Karafoulidou A, Ketikoglou I, Tsantoulas D, Vafiadi I, Hatzis G, Skoutelis A, Akriviadis E, Vasiliadis T,Kitis G, Magiorkinis G, Hatzakis A. Molecular epidemiology of hepatitis C virus(HCV) in Greece: temporal trends in HCV genotype-specific incidence and molecular characterization of genotype 4 isolates. J Viral Hepat. 13:19-27

- Magiorkinis G, Magiorkinis E, Paraskevis D, Vandamme AM, Van Ranst M, Moulton V, Hatzakis A. Phylogenetic analysis of the full-length SARS-CoV sequences: evidence for phylogenetic discordance in three genomic regions. Journal of Medical Virology 74:369-72

Links

http://www.hiv.lanl.gov/content/sequence/HIV/mainpage.html

http://hcv.lanl.gov/content/sequence/HCV/ToolsOutline.html