Retroviruses have been infecting animals for at least 100 million years leaving remnants in their hosts’ genomes known as Endogenous Retroviruses (ERVs). This has resulted into ERVs comprising a significant amount of hosts' genomes. We are interested to understand which factors have affected their abundance within genomes as well as their ability to move between hosts.

Read More: Dynamics of ERVs

As ERVs colonised their hosts' genomes they were subject to an evolutionary trade-off. The intersection of parasite-host co-evolutionary dynamics and the Red Queen race describe parts of this phenomenon. We are interested into which host factors were subject to this evolutionary "Quid-Pro-Quo" as they are likely to be related with antiviral defence and cancer resistance. Animal genome projects provide an invaluable source of primary data for research.

Read More: Host-ERV interface