A consortium to explore the roles human endogenous retroviruses (HERVs) has been selected by Genomics England to be a part of Genomics England Clinical Intepretation Partnership (GeCIP). GeCIP unites both NHS and academic researchers with the aim of translating data from the 100,000 Genomes Project to the healthcare setting, by forming collaborative communities around defined “domains”. The HERV consortium is one part of the functional cross cutting domain, in which genomic functions will be examined across all the 100,000 genomes, rather than concentrating on a specific disease, thus “cross-cutting” across all the available data sets. One focus of the functional cross cutting domain is to catalogue and characterise polymorphisms of ERVs in the whole human genomes of the 100,000 Genomes Project and assess the ways that ERVs are associated with phenotypes (specifically diseases) and other pathophysiological processes.
Read more about the 100,000 Genomes Project and its 30 research domains here: Genomics England Announce Lead Researchers